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ITGB1 anticorps

L’anticorps Souris Monoclonal anti-ITGB1 a été validé pour WB, FACS, IP et Func. Il convient pour détecter ITGB1 dans des échantillons de Humain.
N° du produit ABIN960569

Aperçu rapide pour ITGB1 anticorps (ABIN960569)

Antigène

Voir toutes ITGB1 Anticorps
ITGB1 (Integrin beta 1 (ITGB1))

Reactivité

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Humain

Hôte

  • 173
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Souris

Clonalité

  • 177
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  • 1
Monoclonal

Conjugué

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Cet anticorp ITGB1 est non-conjugé

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Clone

BV7
  • Specificité

    This monoclonal antibody (subclass IgG1) binds to human b1-integrin chain present on tumor cells. BV7 is active on HT-29 colon carcinoma cells and on HCCP-2998 tumor cells. BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells.

    Purification

    Purified

    Immunogène



    Type of Immunogen: Native protein

    Isotype

    IgG1
  • Indications d'application

    Approved: Flo, Func, IP, WB

    Usage: For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For neutralization of biological activity in vitro dilutions have to be made according to the amounts of beta1 integrin to be inactivated.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.1 % BSA

    Stock

    4 °C

    Stockage commentaire

    4°C. Store undiluted.
  • Antigène

    ITGB1 (Integrin beta 1 (ITGB1))

    Autre désignation

    ITGB1 / Integrin Beta 1 / CD29

    Sujet

    Name/Gene ID: ITGB1
    Family: Integrin

    Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta

    ID gène

    3688

    UniProt

    P05556

    Pathways

    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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